CHED 840 |
| Joshua D. Biberdorf, Colin J. Kubarych, and Gordon H. Purser. |
| Thiocyanate ion is prevalent in physiological systems, especially blood plasma. HOCl is an indiscriminate oxidizer produced by neutrophils and will, if left unchecked, lead to tissue damage. Hypothiocyanite (OSCN-), another oxidant, is not as harmful to mammalian cells. Previous research has shown that HOCl rapidly oxidizes thiocyanite to hypothiocyanite. This may limit the amount of time that HOCl is present in the body. However, if HOCl first encounters the amine of a protein, an N-chloro species may first be produced. The kinetics of the reaction between a model N-chloro protein with thiocyanate is the subject of this presentation. The kinetics of the reaction was followed as a function of pH, temperature and reactant concentrations and is the subject of this presentation. |
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Undergraduate Research Poster Session: Environmental Chemistry
2:00 PM-4:00 PM, Monday, 27 March 2006 Georgia World Congress Center -- Ex. Hall B4, Poster
Division of Chemical Education |